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| ISONICOTINIC ACID | ||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 55-22-1 |
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| EINECS NO. |
200-228-2 | |
| FORMULA | C6H5NO2 | |
| MOL WT. | 123.11 | |
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HS CODE |
2933.39 | |
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TOXICITY |
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| SYNONYMS | Pyridine-4-carboxylic Acid; 4-Pyridinecarboxylic acid; | |
| p-Pyridinecarboxylic Acid; Pyridine-carboxylique-4 (French); 4-Picolinic acid; Isonicotinsäure (German); ácido isonicotínico (Spanish); Acide isonicotinique (French); | ||
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | White to off-white crystalline solid | |
| MELTING POINT |
>310 C (sublimes) | |
| BOILING POINT |
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| SPECIFIC GRAVITY |
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| SOLUBILITY IN WATER | ||
| pH | ||
| VAPOR DENSITY |
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NFPA RATINGS |
Health: 1 Flammability: 0 Reactivity: 0 | |
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AUTOIGNITION |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY | Stable under normal conditions | |
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APPLICATIONS |
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| Isonicotinic acid, an isomer of nicotinic acid, is a six-membered ring structure compound composed of five carbon atoms and a nitrogen which replace one carbon-hydrogen unit in the benzene ring, plus a carboxyl side chain at 4-position (nicotinic acid has a carboxyl side chain at 3-position). Isonicotinic acid is chiefly used in antituberculosis drugs especially Isoniazid (isonicotinic acid hydrazide), the most effective one. Isonicotinic acid and its derivatives are used in manufacturing pharmaceuticals and agrochemicals. Niacin acts to reduce plasma cholesterol, as a vasodilator and to treat pellagra. Niacin is used for the prophylaxis. Their derivatives are used for these effects. | ||
| SALES SPECIFICATION | ||
| APPEARANCE | White to off-white crystalline solid | |
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ASSAY |
98.0% max | |
| LOSS ON DRYING | 0.5% max | |
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HEAVY METALS |
20ppm max |
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| RESIDUE ON IGNITION |
0.2% max |
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| TRANSPORTATION | ||
| PACKING | 25kgs in fiber drum | |
| HAZARD CLASS | ||
| UN NO. | ||
| OTHER INFORMATION | ||
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Hazard Symbols: XI, Risk Phrases: 22-36/37/38, Safety Phrases: 26-36/37/39 |
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